What to know about “Ozempic face”
“Ozempic face” is a term for common side effects of the type 2 diabetes medication semaglutide (Ozempic). It can cause sagging and aging of facial skin. A doctor may recommend lifestyle modifications or facial fillers to treat skin and facial side effects.
Novo Nordisk manufactures Ozempic as a medication to treat type 2 diabetes in adults.
Ozempic is available as an injectable pen. Health experts recommend injecting it under the skin of the thigh, upper arm, or abdomen once per week, always on the same day. However, many people take it without a prescription to try to reach their desired body weight. High demand among people who use it off-label is causing a limited supplyTrusted Source in the United States.
This article will explain the term “Ozempic face,” including how Ozempic affects the face, other possible side effects of the medication, and how to avoid the facial effects of Ozempic.Overview
Illustrated by Jason Hoffman
Dr. Paul Jarrod Frank, a cosmetic and celebrity dermatologist, coined the term “Ozempic face” after treating many individuals with this symptom.
How does Ozempic affect the face?
Semaglutide, the generic name for Ozempic, is part of a class of medications known as incretin mimetics. These ensure the pancreas releases sufficient insulin when the blood glucose level is high.
Additionally, Ozempic acts as a long lasting and effective glucagon-like peptide-1 receptor agonist. This means it makes a person feel fuller and delays gastric emptying so they can consume fewer calories.
While Ozempic is safe to use with a doctor’s recommendation, it can cause rapid weight loss that is often more pronounced on the face.
Facial fat serves a protective function and affects facial aesthetics and elasticity. Weight loss can cause dermatological changes and shrinking because the fat that stretches and cushions the skin is no longer in place.
The skin of the face also loses its ability to retract after an episode of rapid weight loss due to reduced levels of elastin and collagen, which are essential for structural integrity.
As a result, people taking Ozempic may report the following facial symptoms:
increased signs of aging, such as more lines and wrinkles
loss of fat, which can lead the skin to become loose and sag
a hollowed-out appearance
lipodystrophy, which affects how the body accumulates and stores fat
Other possible side effects of Ozempic
While Ozempic is safe, its side effects can range from mild to severe. These can include:
nausea
vomiting
diarrhea
flatulence
constipation
stomach ache
abdominal pain
fatigue
injection-site reactions
In rare instances, people may also experience serious adverse effects, including:
vision changes
kidney problems
gall bladder disease
severe allergic reactions
an increased risk of thyroid cancer
low blood sugar, also known as hypoglycemia
inflammation of the pancreas, also known as pancreatitis
Preventing facial side effects
If a person takes Ozempic as a prescription medication, they may be unable to prevent facial side effects. However, if these are a cause for concern, a doctor may recommend any of the following:
reducing the dosage
changing to a different medication
drinking 1–2 liters of water every day
improving protein intake with a protein-rich diet
using dermatological fillers
lifestyle modifications to maintain a healthy weight
If a person decides to stop taking Ozempic, it can take about 5 weeks from the last dose for the drug to clear from their system.
What happens after stopping Ozempic?
A 2022 studyTrusted Source explored changes in body weight and metabolic risk factors among 1,961 participants 1 year after semaglutide treatment.
The authors found that stopping can cause a person to regain lost weight.
After stopping, a person may also notice the following:
increased cravings
an absence of side effects
blood sugar spikes
When to contact a doctor
A person will need to contact a doctor if they experience any severe side effects from taking Ozempic. They can document their symptoms and share them with the doctor.
People should be aware that Ozempic has a boxed warning for thyroid cancer risk. While research indicates it has caused thyroid cancer in animal trials, scientists are unsure if it increases the risk in humans.
Still, a person should speak with the doctor if they experience any of the following symptoms after taking Ozempic:
difficulty swallowing
a lump or pain in the neck
wheezing
shortness of breath
a hoarse voice that worsens over time
Frequently asked questions
Here are some questions people often ask about Ozempic.
Does Ozempic change your face?
Used with a doctor’s guidance, Ozempic can cause rapid weight loss, which can be particularly visible in the face. A sudden loss of fat cells can reduce the appearance of smoothness and fullness in the face, resulting in a gaunt appearance.
What does an Ozempic face look like?
Changes in a person’s face may include:
more lines and wrinkles
loose and sagging skin due to loss of fat cells
a hollowed-out appearance
Does Ozempic age your skin and your face?
When people experience rapid weight loss, their skin does not always shrink at the same time. A lack of fat cells may also affect skin elasticity. Wrinkles and lines, usually associated with aging, can appear.
Summary
Ozempic is a treatment option for people with type-2 diabetes. While Ozempic does not have Food and Drug Administration (FDA) approval for weight management, doctors may prescribe this drug off-label for chronic weight management among those with overweight or obesity. It can cause rapid weight loss and associated facial side effects that some call “Ozempic face.”
Health experts recommend people only use Ozempic as a doctor recommends. If someone experiences severe side effects from taking Ozempic, their doctor may stop prescribing the medication and recommend lifestyle changes.
When a person stops taking Ozempic, they may experience increased food cravings, an absence of side effects, and blood sugar spikes. They may also regain any weight they lost while taking it.10 tips for successful weight loss
10 tips
Losing weight
Overview
A balanced lifestyle and nutritious diet are the key to healthful living and better weight control. Some tips for weight loss include exercising regularly, seeking social support, and keeping a food and weight diary.
According to the Centers for Disease Control and Prevention, around 93.3 million adultsTrusted Source in the United States had obesity in 2015–2016. This number is equivalent to 39.8 percent of the population.
Carrying excess body weight can increase the risk of serious health problems, including heart disease, hypertension, and type 2 diabetes.
Crash diets are not a sustainable solution, whatever perks their proponents might claim them to have. To both lose weight safely and sustain that weight loss over time, it is essential to make gradual, permanent, and beneficial lifestyle changes.
In this article, we provide 10 tips for weight control.
10 tips for successful weight loss
People can lose weight and maintain this loss by taking several achievable steps. These include the following:Healthful meals and snacks should form the foundation of the human diet. A simple way to create a meal plan is to make sure that each meal consists of 50 percent fruit and vegetables, 25 percent whole grains, and 25 percent protein. Total fiber intake should be 25–30 gramsTrusted Source (g) daily.
Eliminate trans fats from the diet, and minimize the intake of saturated fats, which has a strong link with the incidence of coronary heart disease.
Instead, people can consume monounsaturated fatty acids (MUFA) or polyunsaturated fatty acids (PUFA), which are types of unsaturated fat.
The following foods are healthful and often rich in nutrients:
fresh fruits and vegetables
fish
legumes
nuts
seeds
whole grains, such as brown rice and oatmeal
Foods to avoid eating include:
foods with added oils, butter, and sugar
fatty red or processed meats
baked goods
bagels
white bread
processed foods
In some cases, removing certain foods from the diet might cause a person to become deficient in some necessary vitamins and minerals. A nutritionist, dietitian, or another healthcare professional can advise a person how to get enough nutrients while they are following a weight loss program.
2. Keep a food and weight diary
Self-monitoring is a critical factor in successfully losing weight. People can use a paper diary, mobile app, or dedicated website to record every item of food that they consume each day. They can also measure their progress by recording their weight on a weekly basis.
Those who can track their success in small increments and identify physical changes are much more likely to stick to a weight loss regimen.
People can also keep track of their body mass index (BMI) using a BMI calculator.
3. Engage in regular physical activity and exerciseRegular exercise is vital for both physical and mental health. Increasing the frequency of physical activity in a disciplined and purposeful way is often crucial for successful weight loss.
One hour of moderate-intensity activity per day, such as brisk walking, is ideal. If one hour per day is not possible, the Mayo Clinic suggests that a person should aim for a minimum of 150 minutes every week.
People who are not usually physically active should slowly increase the amount of exercise that they do and gradually increase its intensity. This approach is the most sustainable way to ensure that regular exercise becomes a part of their lifestyle.
In the same way that recording meals can psychologically help with weight loss, people may also benefit from keeping track of their physical activity. Many free mobile apps are available that track a person’s calorie balance after they log their food intake and exercise.
If the thought of a full workout seems intimidating to someone who is new to exercise, they can begin by doing the following activities to increase their exercise levels:
taking the stairs
raking leaves
walking a dog
gardening
dancing
playing outdoor games
parking farther away from a building entrance
Individuals who have a low risk of coronary heart disease are unlikely to require medical assessment ahead of starting an exercise regimen.
However, prior medical evaluation may be advisable for some people, including those with diabetes. Anyone who is unsure about safe levels of exercise should speak to a healthcare professional.
4. Eliminate liquid calories
It is possible to consume hundreds of calories a day by drinking sugar-sweetened soda, tea, juice, or alcohol. These are known as “empty calories” because they provide extra energy content without offering any nutritional benefits.
Unless a person is consuming a smoothie to replace a meal, they should aim to stick to water or unsweetened tea and coffee. Adding a splash of fresh lemon or orange to water can provide flavor.
Avoid mistaking dehydration for hunger. An individual can often satisfy feelings of hunger between scheduled meal times with a drink of water.
5. Measure servings and control portions
Eating too much of any food, even low-calorie vegetables, can result in weight gain.
Therefore, people should avoid estimating a serving size or eating food directly from the packet. It is better to use measuring cups and serving size guides. Guessing leads to overestimating and the likelihood of eating a larger-than-necessary portion.
The following size comparisons can be useful for monitoring food intake when dining out:
quarter of a cup is a golf ball
one-half of a cup is a tennis ball
1 cup is a baseball
1 ounce (oz) of nuts is a loose handful
1 teaspoon is 1 playing die
1 tablespoon is a thumb tip
3 oz of meat is a deck of cards
1 slice is a DVD
These sizes are not exact, but they can help a person moderate their food intake when the correct tools are not available.
6. Eat mindfully
Many people benefit from mindful eating, which involves being fully aware of why, how, when, where, and what they eat.
Making more healthful food choices is a direct outcome of becoming more in tune with the body.
People who practice mindful eating also try to eat more slowly and savor their food, concentrating on the taste. Making a meal last for 20 minutes allows the body to register all of the signals for satiety.
It is important to focus on being satisfied after a meal rather than full and to bear in mind that many “all natural” or low-fat foods are not necessarily a healthful choice.
People can also consider the following questions regarding their meal choice:
Is it good “value” for the calorie cost?
Will it provide satiety?
Are the ingredients healthful?
If it has a label, how much fat and sodium does it contain?
7. Stimulus and cue control
Many social and environmental cues might encourage unnecessary eating. For example, some people are more likely to overeat while watching television. Others have trouble passing a bowl of candy to someone else without taking a piece.
By being aware of what may trigger the desire to snack on empty calories, people can think of ways to adjust their routine to limit these triggers.
8. Plan ahead
Stocking a kitchen with diet-friendly foods and creating structured meal plans will result in more significant weight loss.
People looking to lose weight or keep it off should clear their kitchen of processed or junk foods and ensure that they have the ingredients on hand to make simple, healthful meals. Doing this can prevent quick, unplanned, and careless eating.
Planning food choices before getting to social events or restaurants might also make the process easier.
9. Seek social support
Having social support is a great way to stay motivated.
Embracing the support of loved ones is an integral part of a successful weight loss journey.
Some people may wish to invite friends or family members to join them, while others might prefer to use social media to share their progress.
Other avenues of support may include:
a positive social network
group or individual counseling
exercise clubs or partners
employee-assistance programs at work
10. Stay positive
Weight loss is a gradual process, and a person may feel discouraged if the pounds do not drop off at quite the rate that they had anticipated.
Some days will be harder than others when sticking to a weight loss or maintenance program. A successful weight-loss program requires the individual to persevere and not give up when self-change seems too difficult.
Some people might need to reset their goals, potentially by adjusting the total number of calories they are aiming to eat or changing their exercise patterns.
The important thing is to keep a positive outlook and be persistent in working toward overcoming the barriers to successful weight loss.
Losing weight
Successful weight loss does not require people to follow a specific diet plan, such as Slimming World or Atkins. Instead, they should focus on eating fewer calories and moving more to achieve a negative energy balance.
Weight loss is primarily dependent on reducing the total intake of calories, not adjusting the proportions of carbohydrate, fat, and protein in the diet.
A reasonable weight loss goal to start seeing health benefits is a 5–10 percent reduction in body weight over a 6-month time frame.
Most people can achieve this goal by reducing their total calorie intake to somewhere in the range of 1,000–1,600 calories per day.
A diet of fewer than 1,000 calories per day will not provide sufficient daily nutrition.
After 6 months of dieting, the rate of weight loss usually declines, and body weight tends to plateau because people use less energy at a lower body weight. Following a weight maintenance program of healthful eating habits and regular physical activity is the best way to avoid regaining lost weight.
People who have a BMI equal to or higher than 30 with no obesity-related health problems may benefit from taking prescription weight-loss medications. These might also be suitable for people with a BMI equal to or higher than 27 with obesity-related diseases.
However, a person should only use medications to support the above lifestyle modifications. If attempts to lose weight are unsuccessful and a person’s BMI reaches 40 or over, surgical therapy is an option.
Overview
Maintaining weight loss involves a commitment to a healthful lifestyle, from which there is no “vacation.” Although people should feel free to enjoy a special meal out, a birthday celebration, or a joyful holiday feast without feeling guilty, they should try not to stray too far from the path of healthful eating and frequent physical activity.
Those who do may find that they lose focus. Gaining back lost weight is easier than losing it.
Achieving and maintaining weight loss is possible when people adopt lifestyle changes in the long term.
Regardless of any specific methods that help a person lose weight, individuals who are conscious of how and what they eat and engage in daily physical activity or regular exercise will be successful both in losing and keeping off excess weight.
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